By Roger L. Lundblad
A accomplished overview of using biomarkers in diagnostics and prognostics, this ebook covers the heritage and present software of biomarkers, explores the know-how used for the validation and learn of biomarkers, and compares a number of the applied sciences used to spot and degree biomarkers. It investigates the evolution of the underlying know-how and discusses the interpretation of simple technology to medical laboratory use and power advertisement purposes. He additionally covers proteomics and proteomic applied sciences and their purposes within the identity of biomarkers.
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Extra resources for Development and Application of Biomarkers (Protein Science)
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The concept of molecular phenotyping on individual levels, in response to pharmacological intervention, provide the opportunity of clinical trials with n=1 ACE (angiotensin-converting enzyme) phenotyping may be more useful than ACE genotyping as an approach to personalized medicine for ACE inhibitors Use of transcriptional analysis (mRNA analysis via microarray technology) as an approach to the development of a molecular profile (biomarker) for personalized medicine Use of magnetic resonance imaging for identifying biomarkers for late-life depression as an approach to personalized medicine Use of single nucleotide polymorphisms for genotyping in developing a personalized medicine approach to acute macular degeneration The use of targeted imaging uses a radiolabeled probe that binds to specific structural component critical to a single disease or to a more general physiological response, such as inflammation in personalized medicine Current use of chromosomal profile to guide chemotherapy in malignant gliomas is an example of personalized medicine.
Development and Application of Biomarkers (Protein Science) by Roger L. Lundblad