By Roger A. Pedersen
Quantity 34 maintains the sequence' culture of well timed overview and incisive analyses of key examine in developmental biology. not just invaluable to researchers on the leading edge of animal and plant improvement, this quantity is usually a pleasant advent to scholars and execs who're excited by present issues in mobile and molecular mechanisms in improvement.
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Extra info for Current Topics in Developmental Biology, Vol. 34
The first nine cycles of nuclear reproduction last 10 rnin with a replication period of 4 rnin (Kriegstein and Hogness, 1974). Cycles 10-13 last about 15 min, so that it takes just over 2 hr for the first 13 divisions producing -6000 nuclei. The syncytium then undergoes cleavage divisions to produce a cellular blastoderm. The syncytial stages are unique to Drosophila among the four model organisms. Drosophila has a great potential advantage over the other organisms in its wellunderstood and easily manipulated genetics.
Taken from Dimitrov er ul. (1994) with permission. 36 D. Poccia and P. Collas Linker histone analysis is complicated by the absence of a typical H 1. , 1994). Postreplicatively phosphorylated HMG2 and B4 are taken up. , 1994). Chromatin decondensation appears normal and nuclei form with an envelope capable of transport and replication, a lamina, and prereplication centers. No differences are detected from control nuclei. Thus B4 appears not to be essential for chromatin compaction or to provide a scaffold for looped structures involved in replication.
This group represents four different fertilization strategies and encompasses vertebrates and invertebrates. We will examine where data from these four systems are 2. Transfonning Sperm Nuclei into Male Pronuclei 27 in accord and where they are not. We will emphasize recent in vitro results, compare them where possible with the corresponding observations in vivo, and speculate on some unresolved issues. Each organism has unique advantages, and a combination of approaches using these organisms, and hopefully a few others, will extend our ideas about how male pronuclei form and deepen our molecular understanding of how this is achieved.
Current Topics in Developmental Biology, Vol. 34 by Roger A. Pedersen