By Mona Sazgar, Cynthia L. Harden
This textual content provides tricky administration concerns surrounding ladies with epilepsy in a special layout. The Editors offer numerous arguable situations in youth, pre-conception, being pregnant and menopause with invited specialists delivering their differing reviews. The Editors examine the scientific techniques and construct a consensus according to the easiest on hand proof. execs charged with dealing with this difficult sufferer crew might be given insights on delivering the very best care according to present to be had info and specialist opinion.
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Additional resources for Controversies in Caring for Women with Epilepsy: Sorting Through the Evidence
Be cautious about phenytoin, carbamazepine, or other medications with higher risk for toxicity 7. Counsel the patient regarding pregnancy, conception, driving, and seizure safety issues References 1. Pennel PB. Pregnancy, epilepsy and women’s issues. Continuum. 2013;19(3):697–714. 2. Harden CL, Pennel PB. Neuroendocrine considerations in the treatment of men and women with epilepsy. Lancet Neurol. 2013;12(1):72–83. 3. Tomson T, Battino D. Teratogenic effects of antiepileptic drugs. Lancet Neurol.
Author #1 also points out that the current generation of IUDs does not carry the risks of the earlier versions and are highly effective. Both authors discuss the dose-related interactions with topiramate use, with Author #2 elegantly pointing out that “Should we elect to use topiramate in this patient, careful attention must be paid to ﬁnal maintenance dose. It should also be recognized that these are average changes. ” Therefore, it is the unknown interindividual variability in drug interactions that leads us toward a more black-and-white approach.
Veiby G, Engelsen BA, Gilhus NE. Early child development and exposure to antiepileptic drugs prenatally and through breastfeeding: a prospective cohort study on children of women with epilepsy. JAMA Neurol. 2013;70:1367–74. 5. El-Khayat HA, Soliman NA, Tomoum HY, Omram MA, El-Wakad AS, Shatla RH. Reproductive hormonal changes and catamenial pattern in adolescent females with epilepsy. Epilepsia. 2008;49:1619–26. 6. Badawy RA, Vogrin SJ, Lai A, Cook MJ. Are patterns of cortical hyperexcitability altered in catamenial epilepsy?
Controversies in Caring for Women with Epilepsy: Sorting Through the Evidence by Mona Sazgar, Cynthia L. Harden