By Martin Döring, Imme Petersen, Anne Brüninghaus, Regine Kollek
This collective monograph goals at contributing to a higher realizing of the epistemic presumptions, sociocultural implications and traditionally backgrounds of the newly rising and presently increasing strategy of structures biology. In doing so, it deals empirically grounded, useful and reflexive information regarding a paradigmatic shift within the biosciences for a variety of scientists operating within the interdisciplinary parts of structures biology, artificial biology, molecular biology, biology, the philosophy of technology, the sociology of technology and clinical wisdom, technology and expertise reports, know-how review and so on. The authors of this monograph percentage the theoretical methodological premise that technology is a culturally and socially embedded perform which characterizes our tradition as a systematic one and whilst attracts its cutting edge strength from its socio-cultural context. This dialectic dating lies on the center of the present improvement of structures biology that is conceived as a so-called successor of ‘-omics’ learn and caused by means of high-throughput details applied sciences. while a necessity for a holistic conceptualization of complicated organic techniques emerges. The name Contextualizing platforms Biology means that this e-book analyzes the improvement and creation of platforms biology from diverse theoretical and methodological views. We examine numerous contexts starting from the research of cognitive contexts (such as simple theoretical suggestions) to regulative contexts (policies) to the concrete software of a structures biology within the socio-scientific context of a eu learn undertaking. In empirically interpreting those various and interrelated layers and dimensions of platforms biology, the scope of the ebook is going past current makes an attempt to enquire the arrival of latest methods within the organic sciences because it frames and assesses platforms biology from an interdisciplinary and built-in perspective.
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Extra info for Contextualizing Systems Biology: Presuppositions and Implications of a New Approach in Biology
Macmillan, New York, NY Goffman E (1974) Frame analysis: an essay on the organization of experience. Harper and Row, London Goffman E (1981) Forms of talk. University of Pennsylvania Press, Philadelphia, PA Goffman E (1983) Felicity’s condition. Am J Sociol 89(1):1–53 Gomez-Cabrero D, Abugessaisa I, Maier D, Teschendorff A, Merkenschlager M, Gisel A, Ballestar E, Bongcam-Rudloff E, Conesa A, Tegnér J (2014) Data integration in the era of omics: current and future challenges. BMC Syst Biol 8(Suppl 2):I1 Goodman AH, Heath D, Lindee MS (eds) (2003) Genetic nature/culture.
Long live the organism! Perspect Sci 8(3):286–315 Loscalzo J, Barabasi AL (2011) Systems biology and the future of medicine. Wiley Interdiscip Rev Syst Biol Med 3(6):619–627 Lynch M (1993) Scientific practice and ordinary action. Ethnomethodology and social studies of science. Cambridge University Press, Cambridge MacLeod M, Nersessian NJ (2013) The creative industry of integrative systems biology. Mind Soc 12:35–48 Malinowski B (1923) The problem of meaning in primitive languages. In: Ogden CK, Richards IA (eds) The meaning of meaning.
In brief, the folding practices encountered in the human world were metaphorically mapped on the more abstract biological process taking place on the molecular level. As Brown (2008, 25) states, the metaphorical projection of the everyday concept of folding on a molecular biological process provoked a variety of questions that exerted an impact on further experimental arrangements and research undertaken and, at the same time, added an extra shade of meaning to the semantics of the verb “folding”.
Contextualizing Systems Biology: Presuppositions and Implications of a New Approach in Biology by Martin Döring, Imme Petersen, Anne Brüninghaus, Regine Kollek