New PDF release: Biology and Pathology of Astrocyte-Neuron Interactions

By Leif Hertz (auth.), Sergey Fedoroff, Bernhard H. J. Juurlink, Ronald Doucette (eds.)

ISBN-10: 147579486X

ISBN-13: 9781475794861

ISBN-10: 1475794886

ISBN-13: 9781475794885

This quantity is made from papers provided on the moment foreign Altschul Symposium: Biology and Pathology of Astrocyte-Neuron Interactions. The symposium used to be held in Saskatoon, Canada on the collage of Saskatchewn in may well, 1992 in reminiscence of Rudolf Altschul, a graduate of the collage of Prague and a pioneer within the fields of the biology of the vascular and apprehensive platforms. Dr. Altschul used to be Professor and Head of the dep. of Anatomy on the college of Saskatchewan from 1955 to 1963. The Altschul Symposia have been made attainable by means of an endowment left by way of Anni Altschul and via different contributions. The symposia are held biennially. one of many maximum demanding situations for trendy scientists is to discover the mechanisms of mind functionality. even if mobile anatomy of the frightened method has already been good defined and certainly used to be delineated by way of the start of the century, experimental research of the functionality of the mind is comparatively fresh. The framework of the mind is made from stellate cells, the astrocytes, that are interconnected through their methods, therefore featuring a meshwork by which the neurons ship their axons, observed through oligodendrocytes. Microglia are disbursed during the brain.

Show description

Read or Download Biology and Pathology of Astrocyte-Neuron Interactions PDF

Best biology books

Daniel C. Dennett's Darwin's Dangerous Idea: Evolution and the Meanings of Life PDF

In a e-book that's either groundbreaking and obtainable, Daniel C. Dennett, whom Chet Raymo of The Boston Globe calls "one of the main provocative thinkers at the planet," focuses his unerringly logical brain at the thought of ordinary choice, exhibiting how Darwin's nice concept transforms and illuminates our conventional view of humanity's position within the universe. Dennett vividly describes the idea itself after which extends Darwin's imaginative and prescient with impeccable arguments to their usually unbelievable conclusions, hard the perspectives of a few of the main well-known scientists of our day.

Read e-book online Nature's Chemicals: The Natural Products that Shaped Our PDF

Usual items (NPs) is the time period used to explain the loads of millions of chemical substances or elements which are continuously produced by means of residing organisms (plants and microbes). 1000s of hundreds of thousands of a whole lot those chemical compounds are generated each year, and the exchange in exactly some of these has ruled human monetary job for millions of years.

Get Nucleotides and their Receptors in the Nervous System PDF

The learn of purinergic mechanisms has for lengthy been concerned with the activities of the nucleoside adenosine, wherein the contribution of nucleotides to the signaling structures has been underestimated. in line with the court cases of a IUPHAR satellite tv for pc convention held in Leipzig, Germany, this booklet bargains a accomplished replace and evaluation of nucleotide free up, the constitution and serve as of nucleotide receptors, nucleotide-metabolizing ecto-enzymes in addition to the physiological features of nucleotides within the apprehensive procedure.

Extra info for Biology and Pathology of Astrocyte-Neuron Interactions

Example text

13:21-47. , 1986, Electrophysiological properties of astrocytes, in: "Astrocytes", S. Federoff and A. , Academic Press. London. , 1984, The rat optic nerve following enucleation: a pure population of mammalian glia. Abstr. Soc. Neurosci. 10:949. , 1990, Neuroaminidase treatment modifies the function of electroplax sodium channels in planar lipid hi-layers, Neuron 5: 675-684. , 1987, Cytotopographical specialization of enzymatically isolated rabbit retinal Muller cells: K+ conductance of the cell membrane, Glia, 1: 191-197.

Following early demonstrations of Na+ channels in cultured astrocytes, Ritchie and his colleagues (Gray and Ritchie 1985; Bevan et al. 1985) suggested the possibility that astrocytes might function as subsidiary sites for the synthesis of sodium channels which are transferred to the adjacent axon membrane. Cell-to-cell transfer of ion channels has not been demonstrated to date. Thus the idea, that astrocytes synthesize sodium channels destined for transport to the axon, remains speculative. Although astrocyte-to-axon transfer of macromolecules has not yet been demonstrated in mammals, recent experiments have demonstrated that mammalian astrocytes can express Na+ channels with biophysical properties similar to Na+ channels expressed by neurons (Barres et al.

Proton Shifts in WM are Much Smaller than Those in GM Several factors may account for the smaller size of the anoxic acid shift in WM in comparison with GM. First, synapses and SD-like events in GM may have a significant impact on membrane permeability, as was outlined previously. , 1990), and the ion channels that open in spreading depression probably facilitate transmembrane proton fluxes (Kraig and Nicholson, 1978), the absence of these processes in WM could account for its smaller anoxic L1pH0 , just as they help to explain its diminished [M{+]o.

Download PDF sample

Biology and Pathology of Astrocyte-Neuron Interactions by Leif Hertz (auth.), Sergey Fedoroff, Bernhard H. J. Juurlink, Ronald Doucette (eds.)

by Brian

Rated 4.45 of 5 – based on 20 votes