Download e-book for iPad: Bacterial Virulence: Basic Principles, Models and Global by Philippe Sansonetti

By Philippe Sansonetti

ISBN-10: 3527323260

ISBN-13: 9783527323265

Beginning with uncomplicated rules, this reference and instruction manual discusses examples of the main complicated versions of bacterial an infection with reference to their price as paradigms to appreciate the molecular move talks among microbes and their host and tissue objectives. It adopts a really forward-looking, complex technique, putting precise emphasis at the major international demanding situations dealing with scientists this day, resembling pathogenicity vs. commensalisms, infections in immunocompromised hosts and species speci?city issues.Bacterial Virulence: easy rules, versions and worldwide methods is the second one name in Wiley-Blackwell's 'Infection Biology guide Series'. the 1st is Aids and Tuberculosis: a perilous Liaison, edited by way of of the main entire specialists during this quarter, Prof. Dr. Dr. h.c. Stefan Kaufmann on the Max-Planck Institute for infectious illnesses in Berlin, Germany, and Prof. Dr. Bruce Walker, director of the Ragon Institute of MGH, MIT and Harvard in Boston, united states.

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Extra info for Bacterial Virulence: Basic Principles, Models and Global Approaches (Infection Biology (VCH))

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2007) Extraintestinal pathogenic Escherichia coli strains of avian and human origin: link between phylogenetic relationships and common virulence patterns. J. Clin. , 45, 3366–3376. , and Buchrieser, C. (2005) Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83: K24: H31). Microbiology, 151, 385–398. , and Ravel, J. (2008) The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates. J.

160, 1962–1968. , et al. (2001) Helicobacter pylori infection and the development of gastric cancer. N. Engl. J. , 345, 784–789. , et al. (2008) Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-labeled, randomized controlled trial. Lancet, 372, 392–397. , and Nakao, M. (1998) Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology, 115, 642–648. , et al. (1999) Development of poorly differentiated adenocarcinoma and carcinoid due to long-term Helicobacter pylori colonization in Mongolian gerbils.

Interestingly, RegIα production in the gastric mucosal cells is not stimulated directly by H. pylori but by IL-6 in a STAT3dependent manner [30]. Thus, IL-6/IL-11-STAT3 signaling appears to accelerate epithelial cell growth not only directly but also indirectly by stimulating RegIα production in the epithelial cells. We also showed that in addition to IL-6, RegIα production is enhanced by IFNγ, a representative Th1 cytokine [31]. These cytokines appear to be involved in the development of gastric cancer in a coordinated manner.

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Bacterial Virulence: Basic Principles, Models and Global Approaches (Infection Biology (VCH)) by Philippe Sansonetti

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